Post-Ejaculatory Urinalysis (PEU):
When some men ejaculate, some or all of the sperm may travel
back-wards (retrogradely) into the bladder. This can be detected by having a man
first ejaculate into one cup and then urinate into a second one. The urine
following ejaculation is then analyzed for the presence of sperm, which under
normal conditions will not be present.
Anti-sperm Antibodies:
Some men produce antibodies
against their own sperm. These antibod-ies may limit the sperm’s ability to move
through a woman's cervical secretions, block the binding of a sperm to the egg,
or negate the sperm’s ability to penetrate the egg. Men at most risk for
developing antisperm antibodies are those with previous testicular or urological
infection, pre-vious testicular surgery or trauma, or large varicoceles
(varicose veins in the scrotum). Whether these antibodies are present cannot
usually be predicted from a semen analysis or patient history. In many cases,
test-ing for these antibodies is the only way to diagnose this
condition.
White Blood Cells:
Semen may sometimes contain white blood cells due to an infection
or inflammation. Such cells may closely resemble other round cells that are
normally found in the semen, so special testing is required to distinguish them.
Semen cultures may also be performed on a subsequent specimen when the white
blood cell count in the semen is high, to rule out
infection.
Centrifuged (Spun)
Specimen:
Even if there are no sperm present on
the initial semen analysis, there may still be low levels of sperm present that
cannot be visualized by simple techniques. Centrifuging or spinning down the
specimen can determine the presence of any viable sperm in the ejaculate, and
sperm that are con-centrated at the bottom of a test tube to be examined
microscopically.
Fructose:
In cases where no or very low numbers of sperm are found the
semen can be tested for the presence of fructose, to rule out obstruction in the
male genital tract. In some cases sperm is not produced, but in others, blockage
may prevent the sperm from entering the seminal fluid. A pos-itive fructose test
differentiates these two problems.
